They are the reigning Olympic gold medalist and have yet to be defeated in the current Sevens World Series but Aussie Sevens coach Tim Walsh says his team will thrive under the pressure.
Australia will be the team to beat when the Rugby Sevens kicks off this afternoon and Robina Stadium.
"My mother once told me that women are like tea-bags, you never know how strong they are until you drop them in hot water," Walsh said.
"Our girls thrive under pressure and they really look forward to the big moments.
Pressure is something that we embrace and thrive off," he added.
It is the first time Women's Rugby Sevens will be played at the Commonwealth Games with the men's event first being introduced at the 1998 Games in Kuala Lumpur.
Charlotte Caslick is hoping after the success of Rio 2016 and Games on the Gold Coast that it will encourage more kids to play.
"If we can have a successful campaign in Australia, play an exciting brand of rugby and get more boys and girls wanting to play rugby sevens, it's definitely one of our goals," she said.
It will be the last competition for head coach Tim Walsh who announced his resignation from the job in January after five years.
It came as a shock with no one expecting him to depart after being contracted to the end of the 2018 season.
"We just want to just finish the Commonwealth Games off on a high and hopefully send him off the right way," Caslick said.
"He's had an amazing impact on us and for women's sport in general.
"He's been a massive leader just getting us to where we are and on an equal playing field with the men," she said.
Australia opens their campaign against Wales at 5:37pm in Pool B.