The Lions hopes of a third consecutive finals appearance were dashed by a resilient and determined Magpies in front of their home crowd. 

Collingwood's dual coder Ash Brazill stuck to Jess Wuestchner like glue in the opening quarter, which hindered Brisbane's momentum and possession up front. 

The home side was able to continually squashing any balls Brisbane tried to find throughout the game.

Brisbane tried to mount a comeback as their hopes of a top-two spot started to slip away but there were too many wasteful scoring opportunities on their part.

"It's disappointing to lose any week but we had seven scoring shots to two in the second half and had all the play and couldn't capitalise," Brisbane coach Craig Starcevich said post-match.

"The opposition got away a little bit early, but we got our match-ups right about halfway through the second quarter and steadied the ship a bit.

"A lot of scoring and we probably had the game on our terms in the second half and just couldn't finish."

If they were able to convert their chances, it could have made a valuable difference as to who made finals with the Pies only able to score just two points in the final terms.

The result means that Carlton and Geelong will qualify for the finals from Conference B.